HNRNPH3

Across TCGA cell cohorts, HNRNPH3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,568 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible HNRNPH3-associated GO terms across cancer lineages are DNA-templated DNA replication, Regulation of metaphase/anaphase transition of cell cycle, and DNA strand elongation. Each is linked with HNRNPH3 in more than 18 cancer types. Because this analysis shows association rather than direction, both HNRNPH3-to-partner and partner-to-HNRNPH3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated DNA replication grouped by HNRNPH3-low versus HNRNPH3-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HNRNPH3→partner) and Y-score (partner→HNRNPH3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	DNA-templated DNA replication →	+0.117	+1.032	<.001	<.001	3	19
BREAST	Regulation of metaphase/anaphase transition of cell cycle →	+0.116	+0.758	.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	DNA strand elongation →	+0.151	+0.590	.001	.001	3	18
KIDNEY	Regulation of chromosome segregation →	+0.118	+0.736	<.001	.002	3	18
KIDNEY	Positive regulation of cell cycle process →	+0.100	+0.577	<.001	<.001	3	18
KIDNEY	Regulation of chromosome separation →	+0.156	+0.753	<.001	.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,568 associations by consensus.

DNA-templated DNA replication by HNRNPH3 expression — SOFT_TISSUE

Explore this box plot interactively →