HNRNPH2

Across TCGA patient cohorts, HNRNPH2 mutation is significantly associated with the RNA expression of many other genes, with 3,844 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HNRNPH2-associated genes across cancer lineages are RNU1-17P, RNU6-1214P, and RNA5SP198. Each is linked with HNRNPH2 in more than 1 cancer types. Because this analysis shows association rather than direction, both HNRNPH2-to-partner and partner-to-HNRNPH2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU1-17P grouped by HNRNPH2-low versus HNRNPH2-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HNRNPH2→partner) and Y-score (partner→HNRNPH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNU1-17P →	+0.462	+5.103	<.001	.008	3	2
CESC	RNU6-1214P →	+0.425	+5.306	<.001	.006	3	2
CESC	RNA5SP198 →	+0.384	+6.144	<.001	.001	3	2
CESC	RPL17P49 →	+0.136	+6.342	<.001	.001	3	2
CESC	MIR3925 →	+0.798	+6.144	<.001	.001	3	2
SKCM	RNU6-898P →	+0.489	+5.867	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,844 associations by consensus.

RNU1-17P by HNRNPH2 expression — CESC

Explore this box plot interactively →