HNRNPH2

Across TCGA patient cohorts, HNRNPH2 mutation is significantly associated with the total protein of many other genes, with 59 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HNRNPH2-associated genes across cancer lineages are eEF2, p27_pT198, and p62 Lck ligand. Each is linked with HNRNPH2 in more than 1 cancer types. Because this analysis shows association rather than direction, both HNRNPH2-to-partner and partner-to-HNRNPH2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eEF2 grouped by HNRNPH2-low versus HNRNPH2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HNRNPH2→partner) and Y-score (partner→HNRNPH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.293	+1.807	.010	.024	3	2
UCEC	p27_pT198 →	+0.078	+2.700	.022	.006	3	2
UCEC	p62 Lck ligand →	+0.466	+4.087	<.001	<.001	3	2
UCEC	Caspase-8 →	-0.264	-4.365	.001	<.001	3	2
UCEC	c-Met_pY1235 →	+0.070	+1.372	.003	.022	3	2
UCEC	14-3-3_beta →	-0.080	-1.780	.012	.024	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 59 associations by consensus.

eEF2 by HNRNPH2 expression — UCEC

Explore this box plot interactively →