HNRNPH1

Across TCGA pan-cancer cohorts, HNRNPH1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated HNRNPH1 data layer compared with 29 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher HNRNPH1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated HNRNPH1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and COAD show a favorable association.

HNSC, CCRCC, and LUAD are the cancer types where HNRNPH1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Quartile	All	0.166	0.947	.010	52	view →
CCRCC	DFS	Median	III,IV	0.501	0.778	.007	34	view →
LUAD	DFS	Tertile	II,III,IV	1.000	0.212	.005	21	view →
PDAC	OS	Tertile	II,III,IV	0.294	0.645	.002	17	view →
COAD	DFS	Median	All	1.000	0.895	.033	12	view →
LSCC	OS	Quartile	All	0.920	0.742	.035	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

HNRNPH1–HNSC (OS)

Open the HNSC breakdown →