HNRNPH1

Across TCGA patient cohorts, HNRNPH1 mutation is significantly associated with the RNA expression of many other genes, with 953 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HNRNPH1-associated genes across cancer lineages are MIR1226, RNA5SP146, and ANKRD33B-AS1. Each is linked with HNRNPH1 in more than 1 cancer types. Because this analysis shows association rather than direction, both HNRNPH1-to-partner and partner-to-HNRNPH1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR1226 grouped by HNRNPH1-low versus HNRNPH1-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HNRNPH1→partner) and Y-score (partner→HNRNPH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	MIR1226 →	+0.271	+5.584	<.001	.001	3	2
UCEC	RNA5SP146 →	+0.299	+2.332	<.001	.001	3	2
READ	ANKRD33B-AS1 →	+0.187	+6.681	<.001	<.001	3	2
READ	TMEM239 →	+0.021	+5.039	<.001	.008	3	2
CESC	TTTY12 →	+0.044	+4.812	<.001	.006	3	2
UCEC	RNY1P1 →	+0.170	+3.087	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 953 associations by consensus.

MIR1226 by HNRNPH1 expression — LIHC

Explore this box plot interactively →