HNRNPH1

Across TCGA cell cohorts, HNRNPH1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,465 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible HNRNPH1-associated GO terms across cancer lineages are Epigenetic regulation of gene expression, Heterochromatin organization, and Regulation of RNA splicing. Each is linked with HNRNPH1 in more than 19 cancer types. Because this analysis shows association rather than direction, both HNRNPH1-to-partner and partner-to-HNRNPH1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Epigenetic regulation of gene expression grouped by HNRNPH1-low versus HNRNPH1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HNRNPH1→partner) and Y-score (partner→HNRNPH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Epigenetic regulation of gene expression →	+0.069	+1.736	<.001	<.001	3	20
STOMACH	Heterochromatin organization →	+0.060	+0.591	<.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	Regulation of RNA splicing →	+0.090	+1.563	<.001	<.001	3	19
STOMACH	Constitutive heterochromatin formation →	+0.103	+0.782	.003	.005	3	19
BLOOD_Lymphoma	Negative regulation of gene expression, epigenetic →	+0.075	+1.258	<.001	<.001	3	19
PANCREAS	Nuclear transport →	+0.073	+0.966	<.001	.007	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,465 associations by consensus.

Epigenetic regulation of gene expression by HNRNPH1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →