HNRNPF

Across TCGA cell cohorts, HNRNPF RNA expression is significantly associated with the go_rna of many other GO terms, with 3,698 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible HNRNPF-associated GO terms across cancer lineages are Double-strand break repair via nonhomologous end joining, Regulation of meiosis I, and DNA-templated DNA replication. Each is linked with HNRNPF in more than 13 cancer types. Because this analysis shows association rather than direction, both HNRNPF-to-partner and partner-to-HNRNPF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Double-strand break repair via nonhomologous end joining grouped by HNRNPF-low versus HNRNPF-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HNRNPF→partner) and Y-score (partner→HNRNPF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Double-strand break repair via nonhomologous end joining →	+0.050	+0.884	.003	.002	3	14
BONE	Regulation of meiosis I →	+0.180	+0.656	.004	.001	3	12
UPPER_AERODIGESTIVE_TRACT	DNA-templated DNA replication →	+0.132	+1.027	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	DNA replication, removal of RNA primer →	+0.140	+0.883	.006	.002	3	11
BONE	DNA replication initiation →	+0.169	+0.590	.002	.002	3	11
BLOOD_Lymphoma	DNA strand elongation involved in DNA replication →	+0.128	+0.736	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,698 associations by consensus.

Double-strand break repair via nonhomologous end joining by HNRNPF expression — BLOOD_Myeloma

Explore this box plot interactively →