HNRNPF

Across TCGA cell cohorts, HNRNPF mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible HNRNPF-associated genes across cancer lineages are ITGAD, ACER1, and PRAMEF20. Each is linked with HNRNPF in more than 1 cancer types. Because this analysis shows association rather than direction, both HNRNPF-to-partner and partner-to-HNRNPF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ITGAD grouped by HNRNPF-low versus HNRNPF-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HNRNPF→partner) and Y-score (partner→HNRNPF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ITGAD →	+0.011	+3.510	<.001	.003	3	1
LARGE_INTESTINE	ACER1 →	+0.085	+4.145	.002	.001	3	1
LARGE_INTESTINE	PRAMEF20 →	+0.010	+4.022	<.001	.006	3	1
LARGE_INTESTINE	IQCF6 →	+0.228	+3.882	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

ITGAD by HNRNPF expression — LARGE_INTESTINE

Explore this box plot interactively →