HNRNPDL

Across TCGA cell cohorts, HNRNPDL RNA expression is significantly associated with the go_rna of many other GO terms, with 5,263 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible HNRNPDL-associated GO terms across cancer lineages are Regulation of chromosome organization, Sister chromatid segregation, and Regulation of double-strand break repair via homologous recombination. Each is linked with HNRNPDL in more than 18 cancer types. Because this analysis shows association rather than direction, both HNRNPDL-to-partner and partner-to-HNRNPDL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of chromosome organization grouped by HNRNPDL-low versus HNRNPDL-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HNRNPDL→partner) and Y-score (partner→HNRNPDL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Regulation of chromosome organization →	+0.089	+0.815	.001	.004	3	19
SKIN	Sister chromatid segregation →	+0.102	+0.765	<.001	<.001	3	18
BONE	Regulation of double-strand break repair via homologous recombination →	+0.129	+0.719	<.001	.003	3	18
UPPER_AERODIGESTIVE_TRACT	Centrosome duplication →	+0.104	+0.871	<.001	<.001	3	18
OESOPHAGUS	DNA replication →	+0.098	+0.640	.004	.004	3	18
BLOOD_Myeloma	DNA-templated DNA replication →	+0.108	+0.968	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,263 associations by consensus.

Regulation of chromosome organization by HNRNPDL expression — URINARY_TRACT

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