HNRNPCP8

Across TCGA pan-cancer cohorts, HNRNPCP8 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated HNRNPCP8 data layer.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher HNRNPCP8 RNA is associated with better overall survival. In most high-consensus cancer types, elevated HNRNPCP8 expression acts as an unfavorable survival marker, although some lineages such as SKCM and COAD show a favorable association.

SKCM, ACC, and COAD are the cancer types where HNRNPCP8 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	OS	Tertile	II,III,IV	0.814	0.668	.001	72	view →
ACC	OS	Tertile	II,III,IV	0.681	0.956	<.001	64	view →
COAD	OS	Median	All	0.914	0.820	.001	63	view →
LIHC	DFS	Quartile	All	0.401	0.598	.002	22	view →
PCPG	DFS	Median	All	0.855	0.980	<.001	16	view →
PAAD	DFS	Median	All	0.186	0.350	.017	16	view →
MESO	DFS	Quartile	All	0.225	0.391	.001	13	view →
KICH	DFS	Quartile	All	0.637	1.000	.029	12	view →
LGG	DFS	Median	All	0.336	0.457	.013	11	view →
BLCA	OS	Median	All	0.762	0.658	.006	10	view →
UCEC	OS	Tertile	All	0.819	0.900	.011	10	view →
HNSC	OS	Median	II,III,IV	0.494	0.682	.013	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

HNRNPCP8–SKCM (OS)

Open the SKCM breakdown →