Across TCGA patient cohorts, HNRNPCP2 mutation is significantly associated with the total protein of many other genes, with 24 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HNRNPCP2-associated genes across cancer lineages are VHL, NF-kB-p65_pS536, and Smad4. Each is linked with HNRNPCP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both HNRNPCP2-to-partner and partner-to-HNRNPCP2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HNRNPCP2→partner) and Y-score (partner→HNRNPCP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	VHL →	-1.150	-3.459	<.001	.005	3	2
SKCM	NF-kB-p65_pS536 →	+0.401	+2.000	.021	.031	3	1
SKCM	Smad4 →	-0.155	-3.157	.002	.018	3	1
UCEC	eEF2 →	+0.435	+3.169	.006	.019	3	1
UCEC	EGFR_pY1068 →	-0.297	-2.700	.008	.006	3	1
UCEC	ERK2 →	+0.319	+3.169	<.001	.018	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

Exploration

HNRNPCP2 survival (RNA) · tumor vs normal (RNA) · all HNRNPCP2 data types