HNRNPCL1

Across TCGA cell cohorts, HNRNPCL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,213 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible HNRNPCL1-associated GO terms across cancer lineages are Regulation of mRNA catabolic process, RISC complex assembly, and Negative regulation of mRNA splicing, via spliceosome. Each is linked with HNRNPCL1 in more than 8 cancer types. Because this analysis shows association rather than direction, both HNRNPCL1-to-partner and partner-to-HNRNPCL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mRNA catabolic process grouped by HNRNPCL1-low versus HNRNPCL1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HNRNPCL1→partner) and Y-score (partner→HNRNPCL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Regulation of mRNA catabolic process →	+0.037	+0.078	.003	.007	2	9
UPPER_AERODIGESTIVE_TRACT	RISC complex assembly →	+0.089	+0.154	<.001	<.001	3	8
BONE	Negative regulation of mRNA splicing, via spliceosome →	+0.091	+0.161	.003	.004	2	8
PANCREAS	Negative regulation of mRNA processing →	+0.088	+0.095	.001	.002	2	8
BONE	Response to dehydroepiandrosterone →	+0.170	+0.187	.001	.001	3	7
BONE	Transcription pausing by RNA polymerase II →	+0.131	+0.140	.004	.002	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,213 associations by consensus.

Regulation of mRNA catabolic process by HNRNPCL1 expression — BREAST

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