HNRNPCL1

Across TCGA cell cohorts, HNRNPCL1 mutation is significantly associated with the RNA expression of many other genes, with 26 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible HNRNPCL1-associated genes across cancer lineages are TOPAZ1, OR4A16, and OR10J5. Each is linked with HNRNPCL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both HNRNPCL1-to-partner and partner-to-HNRNPCL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TOPAZ1 grouped by HNRNPCL1-low versus HNRNPCL1-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HNRNPCL1→partner) and Y-score (partner→HNRNPCL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	TOPAZ1 →	+0.005	+3.700	<.001	.009	3	1
SKIN	OR4A16 →	+0.416	+3.155	.008	.008	3	1
SKIN	OR10J5 →	+0.011	+3.700	<.001	.009	3	1
SKIN	PRSS55 →	+0.084	+3.297	.001	.002	3	1
SKIN	IL31 →	+0.017	+3.562	<.001	.002	3	1
SKIN	PKHD1L1 →	+0.086	+3.841	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

TOPAZ1 by HNRNPCL1 expression — SKIN

Explore this box plot interactively →