Across TCGA pan-cancer cohorts, HNRNPAB mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated HNRNPAB data layer compared with 29 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher HNRNPAB mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated HNRNPAB expression acts as an unfavorable survival marker, although some lineages such as COAD and PDAC show a favorable association.

COAD, CCRCC, and PDAC are the cancer types where HNRNPAB mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	1.000	0.912	.014	24	view →
CCRCC	DFS	Quartile	III,IV	0.375	0.756	.021	7	view →
PDAC	DFS	Tertile	All	0.845	0.660	.024	4	view →
HNSC	DFS	Quartile	All	0.531	0.759	.034	1	view →
LSCC	DFS	Tertile	II,III,IV	1.000	0.886	.024	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: HNRNPAB tumor-vs-normal RNA expression · all HNRNPAB data types