HNRNPA3P8

Across TCGA pan-cancer cohorts, HNRNPA3P8 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated HNRNPA3P8 data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher HNRNPA3P8 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated HNRNPA3P8 expression acts as an unfavorable survival marker, although some lineages such as LUSC and UCS show a favorable association.

KIRP, UCEC, and ACC are the cancer types where HNRNPA3P8 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Tertile	III,IV	0.408	0.756	.001	138	view →
UCEC	DFS	Tertile	All	0.768	0.868	.001	58	view →
ACC	DFS	Tertile	All	0.225	0.556	.003	49	view →
MESO	DFS	Tertile	IV	0.079	0.414	.004	45	view →
READ	OS	Quartile	IV	0.363	0.834	<.001	41	view →
LUSC	DFS	Quartile	II,III,IV	0.537	0.302	.004	33	view →
UCS	DFS	Median	IV	0.996	0.522	.015	30	view →
KIRC	DFS	Tertile	IV	0.373	0.701	.003	18	view →
CESC	DFS	Tertile	II,III,IV	0.835	0.632	.016	16	view →
BLCA	DFS	Tertile	III,IV	0.304	0.508	.023	15	view →
STAD	OS	Tertile	IV	0.142	0.478	.017	14	view →
LUAD	OS	Quartile	III,IV	0.278	0.570	.019	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

HNRNPA3P8–KIRP (DFS)

Open the KIRP breakdown →