HNRNPA3

Across TCGA patient cohorts, HNRNPA3 mutation is significantly associated with the RNA expression of many other genes, with 524 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HNRNPA3-associated genes across cancer lineages are MTCYBP45, RNU6-34P, and RNA5SP146. Each is linked with HNRNPA3 in more than 1 cancer types. Because this analysis shows association rather than direction, both HNRNPA3-to-partner and partner-to-HNRNPA3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTCYBP45 grouped by HNRNPA3-low versus HNRNPA3-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HNRNPA3→partner) and Y-score (partner→HNRNPA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	MTCYBP45 →	+0.177	+3.934	<.001	.005	3	2
HNSC	RNU6-34P →	+0.293	+5.772	<.001	.001	3	2
UCEC	RNA5SP146 →	+0.291	+2.277	<.001	<.001	3	2
LUSC	LINC00280 →	+0.054	+7.924	<.001	.008	3	2
SKCM	ELOCP32 →	+0.156	+4.771	<.001	.006	3	2
CESC	SMR3B →	+0.054	+4.060	.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 524 associations by consensus.

MTCYBP45 by HNRNPA3 expression — CESC

Explore this box plot interactively →