HNRNPA1P69

Across TCGA pan-cancer cohorts, HNRNPA1P69 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of HNRNPA1P69’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where HNRNPA1P69 RNA is repressed in tumor relative to normal tissue. In most cancer types HNRNPA1P69 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

THCA, KIRC, and HNSC are the cancer types where HNRNPA1P69 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in HNRNPA1P69 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Female	II,III,IV	−0.192	<.001	7	view →
KIRC	All	All	+0.020	.022	4	view →
HNSC	Male	All	+0.056	.004	3	view →
LUAD	All	II,III,IV	+0.048	.043	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

HNRNPA1P69–THCA

Open the THCA breakdown →