Across TCGA pan-cancer cohorts, HNRNPA1P63 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of HNRNPA1P63’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where HNRNPA1P63 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types HNRNPA1P63 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

COAD, LUAD, and THCA are the cancer types where HNRNPA1P63 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in HNRNPA1P63 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	All	+0.140	<.001	8	view →
LUAD	Female	III,IV	+0.087	.008	4	view →
THCA	Male	All	−0.075	.016	2	view →
LUSC	All	All	+0.028	.039	1	view →
KIRC	Male	All	+0.023	.036	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: HNRNPA1P63 RNA expression & survival · all HNRNPA1P63 data types