HNRNPA1P57

Across TCGA patient cohorts, HNRNPA1P57 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,967 significant associations in total. STAD shows the largest number of these associations.

The most reproducible HNRNPA1P57-associated GO terms across cancer lineages are Positive regulation of mRNA metabolic process, Macromolecule methylation, and DNA-templated transcription initiation. Each is linked with HNRNPA1P57 in more than 21 cancer types. Because this analysis shows association rather than direction, both HNRNPA1P57-to-partner and partner-to-HNRNPA1P57 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of mRNA metabolic process grouped by HNRNPA1P57-low versus HNRNPA1P57-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HNRNPA1P57→partner) and Y-score (partner→HNRNPA1P57) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Positive regulation of mRNA metabolic process →	+0.070	+0.344	<.001	<.001	3	22
ESCA	Macromolecule methylation →	+0.067	+0.332	<.001	<.001	3	21
ESCA	DNA-templated transcription initiation →	+0.075	+0.344	<.001	<.001	3	21
ESCA	Regulation of proteasomal ubiquitin-dependent protein catabolic process →	+0.079	+0.328	<.001	<.001	3	21
ESCA	Microtubule-based transport →	+0.048	+0.292	<.001	<.001	2	22
ESCA	Telomere maintenance via telomere lengthening →	+0.077	+0.302	.001	<.001	3	21

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,967 associations by consensus.

Positive regulation of mRNA metabolic process by HNRNPA1P57 expression — ESCA

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