HNRNPA1P52

Across TCGA pan-cancer cohorts, HNRNPA1P52 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated HNRNPA1P52 data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher HNRNPA1P52 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated HNRNPA1P52 expression acts as an unfavorable survival marker, although some lineages such as GBM and PRAD show a favorable association.

KIRP, PCPG, and GBM are the cancer types where HNRNPA1P52 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Median	All	0.504	0.690	<.001	55	view →
PCPG	DFS	Median	All	0.644	0.879	.002	20	view →
GBM	DFS	Tertile	All	0.325	0.177	.004	18	view →
PRAD	DFS	Tertile	All	0.905	0.646	.008	16	view →
UVM	OS	Tertile	III,IV	0.451	1.000	.004	14	view →
HNSC	DFS	Tertile	IV	0.437	0.210	.008	13	view →
LIHC	DFS	Median	All	0.366	0.487	.001	13	view →
KICH	OS	Median	II,III,IV	0.647	0.925	.015	10	view →
PAAD	OS	Median	All	0.465	0.313	.032	10	view →
STAD	DFS	Median	III,IV	0.263	0.545	.025	9	view →
LUSC	OS	Quartile	II,III,IV	0.490	0.217	.008	9	view →
LGG	OS	Tertile	All	0.643	0.393	.002	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

HNRNPA1P52–KIRP (DFS)

Open the KIRP breakdown →