Across TCGA pan-cancer cohorts, HNRNPA1P43 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of HNRNPA1P43’s most consistent transcriptional readouts.
The strongest signal is observed in colon adenocarcinoma (COAD), where HNRNPA1P43 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types HNRNPA1P43 is over-expressed in tumor.
COAD, KIRC, and CHOL are the cancer types where HNRNPA1P43 tumor–normal differential expression is most reproducible.