Across TCGA pan-cancer cohorts, HNRNPA1P34 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of HNRNPA1P34’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where HNRNPA1P34 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types HNRNPA1P34 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.
KIRC, HNSC, and THCA are the cancer types where HNRNPA1P34 tumor–normal differential expression is most reproducible.