HNRNPA1P27

Across TCGA pan-cancer cohorts, HNRNPA1P27 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of HNRNPA1P27’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where HNRNPA1P27 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types HNRNPA1P27 is over-expressed in tumor, although a few such as LUSC and PRAD show the opposite, repressed pattern.

THCA, KIRC, and COAD are the cancer types where HNRNPA1P27 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in HNRNPA1P27 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	IV	+2.675	<.001	11	view →
KIRC	Female	II,III,IV	+0.391	<.001	11	view →
COAD	Female	All	+1.029	<.001	10	view →
LUAD	Female	All	+0.924	<.001	5	view →
LIHC	All	All	+0.130	<.001	5	view →
BRCA	All	All	+0.125	.009	4	view →
LUSC	All	III,IV	−1.333	.003	3	view →
READ	All	All	+0.838	.013	2	view →
PRAD	All	All	−0.260	<.001	2	view →
CHOL	Male	All	+0.251	.030	2	view →
PAAD	Male	All	+0.210	.005	2	view →
KICH	Female	All	−0.219	.004	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

HNRNPA1P27–THCA

Open the THCA breakdown →