HNRNPA1P16

Across TCGA pan-cancer cohorts, HNRNPA1P16 RNA differs between tumor and matched normal tissue in 16 of 18 cancer types tested, making tumor–normal expression one of HNRNPA1P16’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where HNRNPA1P16 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types HNRNPA1P16 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

HNSC, LIHC, and BLCA are the cancer types where HNRNPA1P16 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in HNRNPA1P16 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	III,IV	+0.712	<.001	11	view →
LIHC	Female	II,III,IV	+0.960	<.001	8	view →
BLCA	All	All	+0.904	<.001	8	view →
KIRC	All	All	+0.272	.001	8	view →
KICH	Male	All	−0.892	<.001	7	view →
LUSC	All	All	+0.759	<.001	6	view →
STAD	All	All	+0.453	.003	6	view →
BRCA	All	II,III,IV	+0.304	.001	6	view →
CHOL	Female	All	+2.743	<.001	5	view →
KIRP	All	IV	+1.164	.008	4	view →
THCA	Male	IV	−0.923	<.001	4	view →
ESCA	All	All	+0.553	.001	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 16 lineages.

HNRNPA1P16–HNSC

Open the HNSC breakdown →