HNRNPA1L2

Across TCGA patient cohorts, HNRNPA1L2 mutation is significantly associated with the total protein of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HNRNPA1L2-associated genes across cancer lineages are PRAS40_pT246, Myosin-IIa_pS1943, and Myosin-IIa. Each is linked with HNRNPA1L2 in more than 1 cancer types. Because this analysis shows association rather than direction, both HNRNPA1L2-to-partner and partner-to-HNRNPA1L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRAS40_pT246 grouped by HNRNPA1L2-low versus HNRNPA1L2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HNRNPA1L2→partner) and Y-score (partner→HNRNPA1L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PRAS40_pT246 →	+0.238	+2.820	.024	.036	3	2
UCEC	Myosin-IIa_pS1943 →	+0.350	+2.820	.005	.036	3	1
UCEC	Myosin-IIa →	+0.232	+2.814	.040	.036	3	1
UCEC	p62 Lck ligand →	+0.640	+2.817	.001	.036	2	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

PRAS40_pT246 by HNRNPA1L2 expression — UCEC

Explore this box plot interactively →