HNRNPA1L2

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, HNRNPA1L2 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible HNRNPA1L2-associated genes across cancer lineages are COX4I2, MAGEB4, and OR10W1. Each is linked with HNRNPA1L2 in more than 1 cancer types. Because this analysis shows association rather than direction, both HNRNPA1L2-to-partner and partner-to-HNRNPA1L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, COX4I2 grouped by HNRNPA1L2-low versus HNRNPA1L2-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HNRNPA1L2→partner) and Y-score (partner→HNRNPA1L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_NSCLC_LUADCOX4I2 →+0.098+5.228<.001.00531
LARGE_INTESTINEMAGEB4 →+0.012+5.415.009.00431
LARGE_INTESTINEOR10W1 →+0.022+4.977<.001.00731
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

COX4I2 by HNRNPA1L2 expression — LUNG_NSCLC_LUAD

Box plot of COX4I2 in HNRNPA1L2-low vs HNRNPA1L2-high samples in LUNG_NSCLC_LUAD.

Explore this box plot interactively →

Exploration