HNRNPA0

Across TCGA patient cohorts, HNRNPA0 mutation is significantly associated with the total protein of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HNRNPA0-associated genes across cancer lineages are Notch1, STAT3_pY705, and Tuberin. Each is linked with HNRNPA0 in more than 1 cancer types. Because this analysis shows association rather than direction, both HNRNPA0-to-partner and partner-to-HNRNPA0 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Notch1 grouped by HNRNPA0-low versus HNRNPA0-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HNRNPA0→partner) and Y-score (partner→HNRNPA0) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Notch1 →	+0.262	+3.009	.001	.019	3	1
UCEC	STAT3_pY705 →	-0.542	-3.000	<.001	.037	3	1
UCEC	Tuberin →	+0.317	+3.000	.042	.037	3	1
UCEC	p62 Lck ligand →	+0.508	+2.817	.006	.036	2	1
UCEC	Cyclin-B1 →	+0.774	+3.000	.017	.037	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Notch1 by HNRNPA0 expression — UCEC

Explore this box plot interactively →