HNRNPA0

Across TCGA cell cohorts, HNRNPA0 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible HNRNPA0-associated genes across cancer lineages are BPIFA1, KRTAP12-3, and CENPVL1. Each is linked with HNRNPA0 in more than 1 cancer types. Because this analysis shows association rather than direction, both HNRNPA0-to-partner and partner-to-HNRNPA0 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BPIFA1 grouped by HNRNPA0-low versus HNRNPA0-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HNRNPA0→partner) and Y-score (partner→HNRNPA0) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	BPIFA1 →	+0.134	+5.009	.001	<.001	3	1
LARGE_INTESTINE	KRTAP12-3 →	+0.043	+4.022	<.001	.006	3	1
LARGE_INTESTINE	CENPVL1 →	+0.150	+3.510	<.001	.003	3	1
BREAST	HTR3B →	+0.020	+4.421	<.001	.004	3	1
BREAST	MTRNR2L7 →	+0.019	+4.421	.006	.004	3	1
LARGE_INTESTINE	MNDA →	+0.079	+3.607	<.001	.006	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

BPIFA1 by HNRNPA0 expression — LARGE_INTESTINE

Explore this box plot interactively →