Across TCGA patient cohorts, HMX3 protein abundance is significantly associated with the RNA expression of many other genes, with 277 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible HMX3-associated genes across cancer lineages are CPXM2, PRR12, and PXDN. Each is linked with HMX3 in more than 1 cancer types. Because this analysis shows association rather than direction, both HMX3-to-partner and partner-to-HMX3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HMX3→partner) and Y-score (partner→HMX3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CPXM2 →	+1.676	+1.793	<.001	.004	3	1
BRCA	PRR12 →	-0.634	-1.509	.008	.005	3	1
BRCA	PXDN →	+2.066	+1.779	<.001	.004	3	1
BRCA	PTPRG →	+0.885	+1.509	.009	.005	3	1
BRCA	TIFA →	+0.790	+1.793	.002	.004	3	1
BRCA	BMP6 →	+1.537	+1.509	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 277 associations by consensus.

Exploration

HMX3 survival (RNA) · tumor vs normal (RNA) · all HMX3 data types