Across TCGA cell cohorts, HMX3 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,167 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible HMX3-associated GO terms across cancer lineages are Establishment of spindle orientation, Regulation of cytoplasmic pattern recognition receptor signaling pathway, and Negative regulation of DNA-templated DNA replication. Each is linked with HMX3 in more than 5 cancer types. Because this analysis shows association rather than direction, both HMX3-to-partner and partner-to-HMX3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HMX3→partner) and Y-score (partner→HMX3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Establishment of spindle orientation →	+0.119	+2.220	.001	.006	3	6
SKIN	Regulation of cytoplasmic pattern recognition receptor signaling pathway →	+0.033	+0.488	.001	.002	3	5
PANCREAS	Negative regulation of DNA-templated DNA replication →	+0.087	+0.823	.004	.009	3	5
SOFT_TISSUE	Adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway →	-0.105	-0.429	<.001	.002	3	5
SOFT_TISSUE	Microtubule cytoskeleton organization involved in mitosis →	+0.098	+0.872	<.001	.001	3	5
SOFT_TISSUE	Regulation of chromosome organization →	+0.077	+0.642	<.001	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,167 associations by consensus.

Exploration

HMX3 survival (RNA) · tumor vs normal (RNA) · all HMX3 data types