Across TCGA patient cohorts, HMX2 RNA expression is significantly associated with the mutation status of many other genes, with 10,741 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HMX2-associated genes across cancer lineages are TTN, COL12A1, and TP53. Each is linked with HMX2 in more than 4 cancer types. Because this analysis shows association rather than direction, both HMX2-to-partner and partner-to-HMX2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HMX2→partner) and Y-score (partner→HMX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TTN →	+0.874	+0.344	<.001	<.001	3	5
UCEC	COL12A1 →	+1.446	+0.786	<.001	<.001	3	4
BRCA	TP53 →	+0.598	+0.126	.001	.006	3	4
HNSC	NSD1 →	+2.846	+0.698	<.001	<.001	3	3
LIHC	TLE4 →	+4.178	+0.468	.002	.001	3	3
LIHC	SORCS1 →	+4.178	+0.914	.002	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,741 associations by consensus.

Exploration

HMX2 survival (RNA) · tumor vs normal (RNA) · all HMX2 data types