Across TCGA patient cohorts, HMX1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,667 significant associations in total. LGG shows the largest number of these associations.

The most reproducible HMX1-associated GO terms across cancer lineages are Outer mitochondrial membrane organization, Mitochondrial translation, and RNA 5'-end processing. Each is linked with HMX1 in more than 11 cancer types. Because this analysis shows association rather than direction, both HMX1-to-partner and partner-to-HMX1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HMX1→partner) and Y-score (partner→HMX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Outer mitochondrial membrane organization →	+0.058	+0.274	<.001	<.001	3	12
STAD	Mitochondrial translation →	+0.044	+0.181	<.001	<.001	3	11
STAD	RNA 5'-end processing →	+0.044	+0.228	<.001	<.001	3	11
TGCT	Peptidyl-lysine hydroxylation →	+0.058	+0.821	<.001	<.001	3	10
ESCA	mRNA 3'-splice site recognition →	+0.061	+0.785	<.001	.002	3	10
TGCT	Regulation of non-canonical Wnt signaling pathway →	+0.062	+0.833	<.001	<.001	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,667 associations by consensus.

Exploration

HMX1 survival (RNA) · tumor vs normal (RNA) · all HMX1 data types