Across TCGA cell cohorts, HMX1 RNA expression is significantly associated with the RNA expression of many other genes, with 2,229 significant associations in total. OESOPHAGUS shows the largest number of these associations.

The most reproducible HMX1-associated genes across cancer lineages are C19orf81, PALM, and PDZD4. Each is linked with HMX1 in more than 6 cancer types. Because this analysis shows association rather than direction, both HMX1-to-partner and partner-to-HMX1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HMX1→partner) and Y-score (partner→HMX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	C19orf81 →	+1.578	+1.369	<.001	<.001	3	6
UPPER_AERODIGESTIVE_TRACT	PALM →	+2.330	+0.776	<.001	.004	3	6
BREAST	PDZD4 →	+1.645	+0.792	<.001	<.001	3	6
OESOPHAGUS	SYT3 →	+1.084	+1.145	<.001	<.001	3	6
LUNG_NSCLC_LUSC	JPH3 →	+1.870	+1.151	<.001	.001	3	6
OVARY	BMP7 →	+2.934	+1.128	<.001	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,229 associations by consensus.

Exploration

HMX1 survival (RNA) · tumor vs normal (RNA) · all HMX1 data types