HMSD

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, HMSD RNA expression is significantly associated with the go_rna of many other GO terms, with 3,168 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible HMSD-associated GO terms across cancer lineages are Regulation of post-translational protein modification, Regulation of protein modification by small protein conjugation or removal, and Negative regulation of protein ubiquitination. Each is linked with HMSD in more than 8 cancer types. Because this analysis shows association rather than direction, both HMSD-to-partner and partner-to-HMSD results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HMSD→partner) and Y-score (partner→HMSD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
KIDNEYRegulation of post-translational protein modification →+0.037+1.352.001.00139
KIDNEYRegulation of protein modification by small protein conjugation or removal →+0.057+1.659<.001.00138
BLOOD_LymphomaNegative regulation of protein ubiquitination →+0.056+2.061<.001<.00138
BLOOD_LymphomaResponse to type I interferon →+0.087+2.035<.001<.00138
LUNG_SCLCPositive regulation of protein ubiquitination →+0.049+2.157.007.00638
LARGE_INTESTINESensory perception of sound →-0.082-1.168.001.00428
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,168 associations by consensus.

Exploration