HMOX1

Across TCGA patient cohorts, HMOX1 protein abundance is significantly associated with the RNA expression of many other genes, with 13,275 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HMOX1-associated genes across cancer lineages are MYO1F, CMKLR1, and AIF1. Each is linked with HMOX1 in more than 8 cancer types. Because this analysis shows association rather than direction, both HMOX1-to-partner and partner-to-HMOX1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HMOX1 versus MYO1F in GBM, with a Pearson correlation of 0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HMOX1→partner) and Y-score (partner→HMOX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MYO1F →	+0.984	+0.906	<.001	<.001	3	9
OV	CMKLR1 →	+0.839	+0.557	.001	<.001	3	9
GBM	AIF1 →	+1.103	+0.701	<.001	<.001	3	9
UCEC	CYTH4 →	+0.890	+0.410	<.001	<.001	2	9
UCEC	CSF2RB →	+1.083	+0.398	<.001	<.001	3	8
LUAD	SIRPB1 →	+0.596	+0.391	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,275 associations by consensus.

HMOX1 vs MYO1F — GBM

Explore this scatter interactively →