HMHB1

Across TCGA patient cohorts, HMHB1 RNA expression is significantly associated with the RNA expression of many other genes, with 11,493 significant associations in total. THYM shows the largest number of these associations.

The most reproducible HMHB1-associated genes across cancer lineages are GMFG, TNFRSF4, and LINC01943. Each is linked with HMHB1 in more than 26 cancer types. Because this analysis shows association rather than direction, both HMHB1-to-partner and partner-to-HMHB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HMHB1 versus GMFG in THYM, with a Pearson correlation of 0.88.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HMHB1→partner) and Y-score (partner→HMHB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THYM	GMFG →	+2.394	+2.357	<.001	<.001	3	27
SARC	TNFRSF4 →	+1.451	+0.998	<.001	<.001	3	26
SARC	LINC01943 →	+0.817	+0.690	<.001	<.001	3	23
SCLC	GNGT2 →	+0.966	+0.372	.001	.001	3	21
UCS	C1orf54 →	+0.907	+0.356	.005	<.001	2	22
SARC	CETP →	+1.610	+0.965	<.001	<.001	3	21

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,493 associations by consensus.

HMHB1 vs GMFG — THYM

Explore this scatter interactively →