Across TCGA cell cohorts, HMGN5 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,494 significant associations in total. BONE shows the largest number of these associations.

The most reproducible HMGN5-associated GO terms across cancer lineages are Regulation of tumor necrosis factor superfamily cytokine production, Blood vessel morphogenesis, and Regulation of plasma membrane repair. Each is linked with HMGN5 in more than 7 cancer types. Because this analysis shows association rather than direction, both HMGN5-to-partner and partner-to-HMGN5 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGN5→partner) and Y-score (partner→HMGN5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of tumor necrosis factor superfamily cytokine production →	-0.094	-2.216	<.001	<.001	3	8
BONE	Blood vessel morphogenesis →	-0.106	-2.080	<.001	<.001	3	8
BONE	Regulation of plasma membrane repair →	-0.387	-1.994	<.001	<.001	3	7
BONE	tRNA modification →	+0.056	+2.213	<.001	<.001	3	7
BONE	Regulation of actin filament organization →	-0.073	-1.388	<.001	.008	3	7
BONE	Angiogenesis →	-0.119	-1.777	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,494 associations by consensus.

Exploration

HMGN5 survival (RNA) · tumor vs normal (RNA) · all HMGN5 data types