HMGN3

Across TCGA patient cohorts, HMGN3 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,142 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HMGN3-associated proteins across cancer lineages are PHIP, CDC40, and HMGN3_S78. Each is linked with HMGN3 in more than 5 cancer types. Because this analysis shows association rather than direction, both HMGN3-to-partner and partner-to-HMGN3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HMGN3 versus PHIP in GBM, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGN3→partner) and Y-score (partner→HMGN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PHIP →	+0.379	+0.647	<.001	<.001	3	6
BRCA	CDC40 →	+0.268	+0.684	<.001	<.001	3	5
HNSC	HMGN3_S78 →	+0.627	+0.766	<.001	<.001	3	5
LUAD	MYO6 →	+0.421	+0.667	<.001	<.001	3	4
LSCC	ORC4 →	+0.352	+0.759	<.001	<.001	3	4
HNSC	HMGN3_S93 →	+0.523	+0.987	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,142 associations by consensus.

HMGN3 vs PHIP — GBM

Explore this scatter interactively →