HMGN3-AS1

Across TCGA pan-cancer cohorts, HMGN3-AS1 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated HMGN3-AS1 data layer.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher HMGN3-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated HMGN3-AS1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and READ show a favorable association.

STAD, ACC, and MESO are the cancer types where HMGN3-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	DFS	Median	IV	0.130	0.735	<.001	101	view →
ACC	DFS	Median	All	0.256	0.638	<.001	75	view →
MESO	OS	Median	All	0.432	0.637	<.001	65	view →
LIHC	DFS	Median	All	0.465	0.617	<.001	63	view →
LUAD	OS	Tertile	II,III,IV	0.683	0.409	.005	47	view →
CESC	DFS	Quartile	III,IV	0.249	0.831	.008	32	view →
UCEC	DFS	Quartile	All	0.765	0.873	.007	30	view →
READ	OS	Median	II,III,IV	0.807	0.325	.005	28	view →
CHOL	DFS	Median	II,III,IV	0.121	0.626	.002	27	view →
LAML	DFS	Quartile	All	0.552	0.318	.004	20	view →
KIRP	DFS	Median	IV	0.762	0.044	.021	18	view →
DLBC	DFS	Quartile	All	0.511	1.000	.007	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

HMGN3-AS1–STAD (DFS)

Open the STAD breakdown →