Across TCGA pan-cancer cohorts, HMGN2P8 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of HMGN2P8’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where HMGN2P8 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types HMGN2P8 is over-expressed in tumor.

KIRC, KIRP, and LUAD are the cancer types where HMGN2P8 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in HMGN2P8 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	III,IV	+0.408	<.001	8	view →
KIRP	All	All	+0.130	.046	3	view →
LUAD	All	IV	+0.430	.008	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: HMGN2P8 RNA expression & survival · all HMGN2P8 data types