HMGN2P5

Across TCGA pan-cancer cohorts, HMGN2P5 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated HMGN2P5 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher HMGN2P5 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated HMGN2P5 expression acts as an unfavorable survival marker, although some lineages such as KIRC and SKCM show a favorable association.

ACC, KIRC, and SKCM are the cancer types where HMGN2P5 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.190	0.650	<.001	121	view →
KIRC	OS	Tertile	All	0.718	0.519	<.001	68	view →
SKCM	OS	Median	III,IV	0.516	0.261	<.001	56	view →
LGG	DFS	Median	All	0.303	0.527	<.001	49	view →
COAD	DFS	Median	All	0.779	0.602	<.001	45	view →
PRAD	DFS	Median	All	0.726	0.825	<.001	34	view →
LIHC	DFS	Median	All	0.474	0.625	.003	33	view →
MESO	OS	Median	IV	0.267	0.815	<.001	28	view →
OV	OS	Tertile	IV	0.569	0.294	.011	22	view →
UCEC	OS	Tertile	All	0.846	0.723	.018	22	view →
THYM	OS	Quartile	II,III,IV	0.972	0.636	.003	19	view →
THCA	OS	Median	All	0.986	0.913	.013	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

HMGN2P5–ACC (DFS)

Open the ACC breakdown →