HMGN2P38

Across TCGA pan-cancer cohorts, HMGN2P38 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated HMGN2P38 data layer.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher HMGN2P38 RNA is associated with better overall survival. In most high-consensus cancer types, elevated HMGN2P38 expression acts as an unfavorable survival marker, although some lineages such as SKCM and UCS show a favorable association.

SKCM, UVM, and LIHC are the cancer types where HMGN2P38 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	OS	Tertile	All	0.839	0.751	<.001	74	view →
UVM	OS	Tertile	All	0.452	0.946	<.001	54	view →
LIHC	DFS	Tertile	All	0.297	0.470	.001	43	view →
LUSC	DFS	Tertile	III,IV	0.401	0.948	.002	39	view →
LGG	DFS	Quartile	All	0.712	0.860	.004	20	view →
UCS	DFS	Tertile	IV	0.996	0.475	.018	18	view →
MESO	OS	Median	III,IV	0.466	0.647	.032	17	view →
READ	DFS	Tertile	III,IV	0.509	0.828	.008	15	view →
STAD	DFS	Tertile	IV	0.134	0.646	<.001	12	view →
COAD	OS	Quartile	All	0.970	0.835	.024	12	view →
KIRC	DFS	Median	III,IV	0.740	0.562	.028	10	view →
CESC	OS	Tertile	All	0.940	0.812	.006	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

HMGN2P38–SKCM (OS)

Open the SKCM breakdown →