Across TCGA pan-cancer cohorts, HMGN2P36 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of HMGN2P36’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where HMGN2P36 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types HMGN2P36 is over-expressed in tumor, although a few such as KICH and KIRP show the opposite, repressed pattern.

COAD, UCEC, and KICH are the cancer types where HMGN2P36 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in HMGN2P36 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	All	+0.292	.002	4	view →
UCEC	All	All	+0.233	.024	2	view →
KICH	All	II,III,IV	−0.042	.033	2	view →
KIRP	All	All	−0.036	.022	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: HMGN2P36 RNA expression & survival · all HMGN2P36 data types