Across TCGA pan-cancer cohorts, HMGN2P30 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of HMGN2P30’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where HMGN2P30 RNA is repressed in tumor relative to normal tissue. In most cancer types HMGN2P30 is over-expressed in tumor, although a few such as THCA and LUSC show the opposite, repressed pattern.

THCA, BRCA, and LUSC are the cancer types where HMGN2P30 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in HMGN2P30 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	All	−0.146	.003	5	view →
BRCA	All	All	+0.280	.005	4	view →
LUSC	All	III,IV	−0.233	.013	2	view →
COAD	All	All	+0.164	.013	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: HMGN2P30 RNA expression & survival · all HMGN2P30 data types