HMGN2P26

Across TCGA pan-cancer cohorts, HMGN2P26 RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated HMGN2P26 data layer.

The strongest signal is observed in thymoma (THYM), where higher HMGN2P26 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated HMGN2P26 expression acts as an unfavorable survival marker.

THYM, OV, and HNSC are the cancer types where HMGN2P26 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THYM	OS	Tertile	III,IV	0.103	0.944	<.001	72	view →
OV	OS	Tertile	II,III,IV	0.202	0.330	.014	60	view →
HNSC	OS	Tertile	III,IV	0.350	0.667	.008	45	view →
BLCA	OS	Tertile	All	0.097	0.688	<.001	36	view →
ESCA	OS	Tertile	IV	0.095	0.512	.008	36	view →
KIRC	DFS	Tertile	IV	0.127	0.619	.008	36	view →
MESO	OS	Tertile	III,IV	0.289	0.583	.043	18	view →
TGCT	DFS	Tertile	All	0.385	0.811	.005	18	view →
PRAD	DFS	Tertile	All	0.769	0.937	.013	18	view →
LUAD	DFS	Tertile	IV	0.223	0.710	.043	18	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

HMGN2P26–THYM (OS)

Open the THYM breakdown →