HMGN2P20

Across TCGA pan-cancer cohorts, HMGN2P20 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated HMGN2P20 data layer.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher HMGN2P20 RNA is associated with better overall survival. In most high-consensus cancer types, elevated HMGN2P20 expression acts as an unfavorable survival marker, although some lineages such as SKCM and HNSC show a favorable association.

SKCM, BRCA, and READ are the cancer types where HMGN2P20 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	OS	Tertile	III,IV	0.858	0.643	<.001	77	view →
BRCA	DFS	Tertile	All	0.570	1.000	.033	36	view →
READ	OS	Tertile	IV	0.378	0.955	<.001	27	view →
HNSC	DFS	Quartile	All	0.452	0.290	.003	22	view →
MESO	OS	Tertile	IV	0.155	0.624	.004	18	view →
LIHC	OS	Tertile	III,IV	0.059	0.738	<.001	18	view →
UVM	OS	Tertile	All	0.387	0.730	.023	12	view →
GBM	DFS	Quartile	All	0.391	0.171	.018	9	view →
BLCA	DFS	Tertile	IV	0.211	0.563	.001	9	view →
STAD	OS	Median	II,III,IV	0.703	0.422	.026	7	view →
THYM	DFS	Tertile	All	1.000	0.784	.019	7	view →
OV	OS	Quartile	III,IV	0.383	0.288	.026	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

HMGN2P20–SKCM (OS)

Open the SKCM breakdown →