HMGN2P11

Across TCGA patient cohorts, HMGN2P11 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,782 significant associations in total. STAD shows the largest number of these associations.

The most reproducible HMGN2P11-associated GO terms across cancer lineages are Positive regulation of cell cycle process, Regulation of chromosome segregation, and Regulation of DNA-templated DNA replication. Each is linked with HMGN2P11 in more than 18 cancer types. Because this analysis shows association rather than direction, both HMGN2P11-to-partner and partner-to-HMGN2P11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of cell cycle process grouped by HMGN2P11-low versus HMGN2P11-high in DLBC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGN2P11→partner) and Y-score (partner→HMGN2P11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	Positive regulation of cell cycle process →	+0.042	+0.132	.001	<.001	2	19
DLBC	Regulation of chromosome segregation →	+0.064	+0.128	.002	.006	2	17
ESCA	Regulation of DNA-templated DNA replication →	+0.063	+0.161	.003	.009	1	18
STAD	Positive regulation of cell cycle phase transition →	+0.031	+0.082	<.001	<.001	3	16
ESCA	Regulation of DNA damage checkpoint →	+0.059	+0.204	.001	<.001	2	17
DLBC	Positive regulation of mitotic cell cycle →	+0.040	+0.148	.007	.002	2	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,782 associations by consensus.

Positive regulation of cell cycle process by HMGN2P11 expression — DLBC

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