Across TCGA cell cohorts, HMGN2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,074 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible HMGN2-associated GO terms across cancer lineages are Negative regulation of ubiquitin protein ligase activity, Positive regulation of chromosome condensation, and Meiotic sister chromatid cohesion. Each is linked with HMGN2 in more than 18 cancer types. Because this analysis shows association rather than direction, both HMGN2-to-partner and partner-to-HMGN2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGN2→partner) and Y-score (partner→HMGN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Negative regulation of ubiquitin protein ligase activity →	+0.258	+1.064	.001	<.001	3	19
OESOPHAGUS	Positive regulation of chromosome condensation →	+0.250	+1.373	<.001	<.001	3	19
BLOOD_Myeloma	Meiotic sister chromatid cohesion →	+0.121	+0.834	<.001	.002	3	19
OESOPHAGUS	Mitotic metaphase chromosome alignment →	+0.123	+1.126	.002	<.001	3	18
OESOPHAGUS	Regulation of mitotic nuclear division →	+0.148	+1.151	.001	<.001	3	18
OESOPHAGUS	Regulation of mitotic sister chromatid separation →	+0.211	+1.276	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,074 associations by consensus.

Exploration

HMGN2 survival (RNA) · tumor vs normal (RNA) · all HMGN2 data types