HMGN1P9

Across TCGA pan-cancer cohorts, HMGN1P9 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated HMGN1P9 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher HMGN1P9 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated HMGN1P9 expression acts as an unfavorable survival marker, although some lineages such as TGCT and LGG show a favorable association.

ACC, SKCM, and THCA are the cancer types where HMGN1P9 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Tertile	All	0.133	0.686	.004	54	view →
SKCM	OS	Tertile	All	0.092	0.326	.001	39	view →
THCA	OS	Tertile	IV	0.720	1.000	.004	36	view →
PCPG	DFS	Tertile	All	0.079	0.863	<.001	36	view →
COAD	DFS	Tertile	All	0.502	0.731	<.001	18	view →
LUSC	DFS	Tertile	III,IV	0.121	0.784	.002	18	view →
READ	DFS	Tertile	IV	0.224	0.686	.005	15	view →
TGCT	DFS	Quartile	All	0.911	0.573	.001	14	view →
LUAD	DFS	Tertile	IV	0.502	0.767	.031	12	view →
LGG	OS	Tertile	All	0.951	0.844	.003	10	view →
GBM	DFS	Tertile	All	0.630	0.237	.013	9	view →
PRAD	OS	Quartile	All	0.967	0.995	.011	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

HMGN1P9–ACC (OS)

Open the ACC breakdown →