HMGN1P36

Across TCGA pan-cancer cohorts, HMGN1P36 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of HMGN1P36’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where HMGN1P36 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types HMGN1P36 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

BLCA, LUAD, and KICH are the cancer types where HMGN1P36 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in HMGN1P36 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	Male	III,IV	+1.418	<.001	8	view →
LUAD	Male	II,III,IV	+0.777	<.001	8	view →
KICH	Female	All	−1.040	<.001	7	view →
LUSC	Male	II,III,IV	+0.775	<.001	7	view →
BRCA	All	All	+0.790	<.001	6	view →
LIHC	All	All	+0.369	<.001	6	view →
HNSC	All	All	+0.316	.007	5	view →
CHOL	All	All	+0.703	.002	2	view →
STAD	All	All	+0.360	.017	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

HMGN1P36–BLCA

Open the BLCA breakdown →